Are you looking for a safe and effective solution to terminate unwanted pregnancies in your pets? Look no further than Alizin for dogs. This medication is specifically designed to provide a non-surgical option for terminating pregnancies in dogs and cats. In addition to its use for pregnancy termination, Alizin is also used to treat pyometra in dogs and cats. Read on to learn more about this trusted solution for pet owners.
Composition and Form of Release
Alizin contains 30 mg of aglepristone as the active substance per 1 ml of the drug. It is available in a 10 ml pack, sealed in glass vials with chlorobutanol caps and aluminum caps. The solution is a clear yellow liquid meant for subcutaneous injection.
Pharmacological Properties
Aglepristone, the main component of Alizin, is a synthetic steroid that acts as a progesterone antagonist. By blocking the progesterone receptors in the uterus, Alizin disrupts the normal physiological process of maintaining pregnancy in dogs and cats. This disruption leads to abortion or fetal resorption. Aglepristone has a higher affinity for progesterone receptors in the uterus compared to progesterone itself. It does not affect the levels of progesterone, prostaglandins, oxytocin, or cortisol in the blood. However, it does promote the release of prolactin. Aglepristone is primarily metabolized in the liver and excreted through feces.
Indications
Alizin is primarily used to terminate unwanted pregnancies in dogs and cats up to 45 days after accidental mating. It is also an effective treatment for pyometra in dogs and cats without the need for surgery.
Dosage and Administration
For dogs, Alizin is administered after the end of the heat period. It should be given subcutaneously in the withers, twice, with a 24-hour interval between doses. The recommended dosage is 10 mg per kg of the animal’s weight. For cats, a single dose of 10 mg per kg of body weight is administered every 24 hours. If the volume of the injected solution exceeds 5 ml, it should be administered at different points. The effectiveness of Alizin is 99% when used before the 25th day of gestation and 96% when used before the 45th day. Abortion or fetal resorption typically occurs within 7 days after Alizin administration. It is advised to schedule a follow-up visit after treatment to confirm the termination of pregnancy through ultrasound examination.
Side Effects and Contraindications
In some animals, allergic reactions may occur due to increased individual sensitivity to Alizin. Local inflammation and pain at the injection site are also possible side effects. Bitches treated after the twentieth day of pregnancy may experience signs of physiological childbirth, such as fetus expulsion, slight loss of appetite, and milk stagnation. Alizin should not be used in animals with individual hypersensitivity to aglepristone or those with impaired liver, kidney, or adrenal gland function. Diabetic animals should also avoid using this medication.
Storage and Safety
To ensure the integrity of the product, store Alizin in the original sealed package. Keep it in a dry place protected from light, away from the reach of children and animals, and separate from food and feed. The recommended storage temperature is between 15°C and 25°C. The shelf life of Alizin is three years from the date of manufacture, and once opened, it should be used within 28 days under aseptic conditions and stored at a temperature of 3°C to 8°C.
Frequently Asked Questions
Q: Can Alizin be used for dogs and cats?
A: Yes, Alizin is suitable for both dogs and cats. It can be used to terminate unwanted pregnancies in both species.
Q: How long does it take for Alizin to terminate a pregnancy?
A: Abortion or fetal resorption typically occurs within 7 days after Alizin administration.
Q: Can Alizin be used to treat pyometra in dogs and cats?
A: Yes, Alizin is an effective treatment for pyometra in dogs and cats without the need for surgery.
Conclusion
When it comes to finding a safe and reliable solution for terminating unwanted pregnancies in dogs and cats, Alizin is a trusted choice. This non-surgical option provides pet owners with peace of mind and a safe outcome. With its precise composition and proven efficacy, Alizin offers an effective method for terminating pregnancies and treating pyometra. Keep your pets healthy and happy with Alizin, the trusted brand for reproductive health care for your furry friends.
For more information on Alizin and other pet health products, visit Pawsoha.